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Direct detection of novel expanded trinucleotide repeats in the human genome

โœ Scribed by Schalling, Martin; Hudson, Thomas J.; Buetow, Kenneth H.; Housman, David E.


Book ID
109916198
Publisher
Nature Publishing Group
Year
1993
Tongue
English
Weight
563 KB
Volume
4
Category
Article
ISSN
1061-4036

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Direct detection of expanded trinucleoti
โœ Petronis, Arturas; Heng, Henry H. Q.; Tatuch, Yuriy; Shi, Xiao-Mei; Klempan, Tim ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 24 KB ๐Ÿ‘ 1 views

Recently, unstable trinucleotide repeats have been shown to be the etiologic factor in seven neuropsychiatric diseases, and they may play a similar role in other genetic disorders which exhibit genetic anticipation. We have tested one polymerase chain reaction (PCR)-based and two hybridizationbased