Direct detection of expanded trinucleoti
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Petronis, Arturas; Heng, Henry H. Q.; Tatuch, Yuriy; Shi, Xiao-Mei; Klempan, Tim
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Article
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1996
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John Wiley and Sons
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English
โ 24 KB
๐ 1 views
Recently, unstable trinucleotide repeats have been shown to be the etiologic factor in seven neuropsychiatric diseases, and they may play a similar role in other genetic disorders which exhibit genetic anticipation. We have tested one polymerase chain reaction (PCR)-based and two hybridizationbased