Innovative study design for paediatric clinical trials
β Scribed by Paola Baiardi; Carlo Giaquinto; Silvia Girotto; Cristina Manfredi; Adriana Ceci; on behalf of the TEDDY Network of Excellence
- Publisher
- Springer
- Year
- 2011
- Tongue
- English
- Weight
- 232 KB
- Volume
- 67
- Category
- Article
- ISSN
- 0031-6970
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
In this issue of the Annals, Sachdeo and colleagues report on the efficacy of felbamate for partial onset seizures. They utilized a vahd active treatment control design, which was designed to show and did show a difference in efficacy 11). These results may be consid-
## Abstract A twoβstage design is proposed to choose among several experimental treatments and a standard treatment in clinical trials. The first stage employs a selection procedure to select the best treatment, provided it is better than the standard. The second stage tests the hypothesis between