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Innovations in the design of clinical trials in breast cancer

โœ Scribed by Marvin Zelen

Publisher
Springer US
Year
1983
Tongue
English
Weight
585 KB
Volume
3
Category
Article
ISSN
0167-6806

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Clinical trial of nafoxidine in advanced
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โœ Steinbaum, Fred L. ;de Jager, Robert L. ;Krakoff, Irwin H. ๐Ÿ“‚ Article ๐Ÿ“… 1978 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 198 KB

Forty-nine postmenopausal patients with advanced breast cancer were treated with a nonsteroidal antiestrogen, Nafoxidine. The drug was generally well tolerated with dermatitis being the major toxic effect. A partial response in 12 of 40 patients, or 30%, was achieved with a median duration of respon