Clinical trial of nafoxidine in advanced breast cancer

✍ Scribed by Steinbaum, Fred L. ;de Jager, Robert L. ;Krakoff, Irwin H.

• Publisher: John Wiley and Sons
• Year: 1978
• Tongue: English
• Weight: 198 KB
• Volume: 4
• Category: Article
• ISSN: 0098-1532
• DOI: 10.1002/mpo.2950040207

✦ Synopsis

Forty-nine postmenopausal patients with advanced breast cancer were treated with a nonsteroidal antiestrogen, Nafoxidine. The drug was generally well tolerated with dermatitis being the major toxic effect. A partial response in 12 of 40 patients, or 30%, was achieved with a median duration of response of greater than five months.