## Abstract The neurodegenerative process is well established in Parkinson patients presenting to a physician with early motor signs. There is increasing evidence that a variety of nonmotor features can antedate the typical presentation by many years. As the search for successful diseaseβmodifying
Innovative monotherapy trial designs for the assessment of antiepileptic drugs: a critical appraisal
β Scribed by E. Perucca
- Publisher
- Springer
- Year
- 1998
- Tongue
- English
- Weight
- 183 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0031-6970
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
To assess the efficacy of CM40907 -a new antiepileptic drug -in suppressing inter-ictai spikes, 6 patients with severe intractable epilepsy and frequent spikes in their inter-ictal EEGs were entered in a double-blind placebo-controlled trial. The results show that CM40907 is efficacious in reducing
The ICH guideline on photostability (ICH Topic Q1B) was published in November 1996 and has been implemented in all three regions (US, EU, and Japan). The guideline describes a useful basic protocol for testing of new drug substances and associated drug products for manufacturing, storage, and distri