✦ LIBER ✦
Suppression of inter-ictal spikes by CM40907. A double-blind placebo-controlled investigation and review of spike counting as a methodology for assessing the antiepileptic effect of drugs
✍ Scribed by R. Yepez-Lasso; J.S. Duncan; S.D. Shorvon
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 409 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0920-1211
No coin nor oath required. For personal study only.
✦ Synopsis
To assess the efficacy of CM40907 -a new antiepileptic drug -in suppressing inter-ictai spikes, 6 patients with severe intractable epilepsy and frequent spikes in their inter-ictal EEGs were entered in a double-blind placebo-controlled trial. The results show that CM40907 is efficacious in reducing spike counts in the first hour after oral administration. The results of the study are pre.sented and inter-ictal spike counting as a method is discussed.