## Abstract **Carbohydrates are slippery customers** in water. Camouflaged by solvent‐mimicking hydroxy groups, they make challenging targets, even for natural receptors. In their Communication on page 1775 ff., A. P. Davis and co‐workers describe a synthetic receptor that is remarkably effective f
✦ LIBER ✦
Innentitelbild: A Synthetic Lectin for O-Linked β-N-Acetylglucosamine (Angew. Chem. 10/2009)
✍ Scribed by Yann Ferrand; Emmanuel Klein; Nicholas P. Barwell; Matthew P. Crump; Jesus Jiménez-Barbero; Cristina Vicent; Geert-Jan Boons; Sampat Ingale; Anthony P. Davis
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 531 KB
- Volume
- 121
- Category
- Article
- ISSN
- 0044-8249
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## Abstract **Changing employment**: Receptor **1** binds β‐__N__‐acetylglucosaminyl (β‐GlcNAc) up to 100 times more strongly than it does glucose. This synthetic lectin shows affinities similar to wheat germ agglutinin (WGA), a natural lectin used to bind GlcNAc. Remarkably, **1** is more selectiv