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Innate and adaptive autoimmunity in type 1 diabetes

✍ Scribed by Michael P Morran; Marcia F McInerney; Massimo Pietropaolo

Book ID
110905537
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
142 KB
Volume
9
Category
Article
ISSN
1399-543X

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πŸ“œ SIMILAR VOLUMES

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Insulin dependent diabetes mellitus is a T-cell mediated autoimmune disease. Several &cell antigens, mostly non-tissue-specific, have been implicated in the disease process. The antigens and the autoimmune T cells exist in healthy individuals, as do many of the genes required for the development of

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## Abstract Two arms of the immune system, innate and adaptive immunity, differ in their mode of immune recognition. The innate immune system recognizes a few highly conserved structures on a broad range of microorganisms. On the other hand, recognition of self or autoreactivity is generally confin