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Initial responses of a clonal osteoblast-like cell line, MOB 3–4, to phosphatidic acid in vitro

✍ Scribed by Kawase, Tomoyuki; Suzuki, Akitoshi


Book ID
123542720
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
500 KB
Volume
10
Category
Article
ISSN
0169-6009

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Effects of prostaglandin E2 and F2α on c
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Prostaglandin E, (PGE,, 5 ng/ml to 5 pg/ml) induced a dose-dependent increase in cAMP accumulation, inositol phosphates (IPS) accumulation, and cytoplasmic free Ca2+ ([Ca2+li) in a clonal osteoblast-like cell line, MOB 3-4. In contrast, prostaglandin F,a (PGF a, 5 ng/ml to 5 p,g/ml) stimulated incre