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Starvation of a clonal osteoblast-like cell line, MOB 3-4-F2, down-regulates prostaglandin E2 receptors but increases cAMP response to prostaglandin E2

โœ Scribed by Tomoyuki Kawase; Michiaki Orikasa; Akitoshi Suzuki


Book ID
113388396
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
452 KB
Volume
3
Category
Article
ISSN
0898-6568

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Effects of prostaglandin E2 and F2ฮฑ on c
โœ Tomoyuki Kawase; Michiaki Orikasa; Akitoshi Suzuki ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 816 KB

Prostaglandin E, (PGE,, 5 ng/ml to 5 pg/ml) induced a dose-dependent increase in cAMP accumulation, inositol phosphates (IPS) accumulation, and cytoplasmic free Ca2+ ([Ca2+li) in a clonal osteoblast-like cell line, MOB 3-4. In contrast, prostaglandin F,a (PGF a, 5 ng/ml to 5 p,g/ml) stimulated incre