𝔖 Bobbio Scriptorium
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Inhibitory RNA Ligand to Reverse Transcriptase from Feline Immunodeficiency Virus †

✍ Scribed by Chen, Hang; McBroom, Douglas G.; Zhu, Ya-Qi; Gold, Larry; North, Thomas W.


Book ID
126960751
Publisher
American Chemical Society
Year
1996
Tongue
English
Weight
474 KB
Volume
35
Category
Article
ISSN
0006-2960

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By bioactive-guided fractionation of a water extract of Cordia spinescens, magnesium lithospermate (1), calcium rosmarinate (2) and magnesium rosmarinate (3) were isolated as potent inhibitory substances against HIV-1 reverse transcriptase (RT) with IC 50 values of 0.8, 5.8 and 3.1 M, respectively.