Topoisomerase I dissociates human immunodeficiency virus type 1 reverse transcriptase from genomic RNAs
β Scribed by Hidehiro Takahashi; Hirofumi Sawa; Hideki Hasegawa; Kazuo Nagashima; Tetsutaro Sata; Takeshi Kurata
- Book ID
- 116287726
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 182 KB
- Volume
- 313
- Category
- Article
- ISSN
- 0006-291X
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We describe a gene system allowing the facile production of multiply substituted reverse transcriptases (RTs), the enzymatic characterization of these purified RTs, and the study of these mutations in the defined genetic background of the macrophagetropic, non-laboratory-adapted human immunodeficien