Inhibitory Effects of 1-Deazaadenosine Analogues on HIV Replication and Adenosine Deaminase
✍ Scribed by Vittori, Sauro; Volpini, Rosaria; Camaioni, Emidio; Palúg, Giorgio; Cristalli, Giorgio
- Book ID
- 127297321
- Publisher
- Taylor and Francis Group
- Year
- 1995
- Tongue
- English
- Weight
- 187 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0732-8311
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Forty-eight methanol and aqueous extracts from Sudanese plants were screened for their inhibitory activity on viral replication. Nineteen extracts showed inhibitory effects on HIV-induced cytopathic effects (CPE) on MT-4 cells. The extracts were further screened against HIV-1 protease (PR) using an