Inhibitory effect of androgens on DMBA-induced mammary carcinoma in the rat
✍ Scribed by Sophie Dauvois; Shengmin Li; Céline Martel; Fernand Labrie
- Publisher
- Springer US
- Year
- 1989
- Tongue
- English
- Weight
- 660 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0167-6806
No coin nor oath required. For personal study only.
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## Abstract The present paper reports the inhibitory effect of __Asparagus racemosus__on DMBA‐induced mammary tumorigenesis in rats of Holtzman strain. When virgin female rats, normal or primed with 17‐β‐estradiol treatment, are put on diets containing 0.25%, 0.5%, 1% or 2% __Asparagus__ root extra
Only a small proportion of DMBA-induced rat mammary tumors are transplantable in cleared (gland-free) mammary fat pads. To enhance their transplantability, several host factors were modified: age, parity, hormone levels, and tissue integrity of the fat pad. Our 2 important findings were that (I) the