The novel anti-estrogen EM-800 and medroxyprogesterone acetate (MPA) inhibit estrone (E 1 )-stimulated growth of dimethylbenz[a]anthracene (DMBA)-induced mammary tumors in a rat model. After 65 days, ovariectomy (OVX) decreased total tumor area to 9.6 ؎ 3.9% of initial size, while E 1 (1.0 µg, s.c.,
✦ LIBER ✦
Inhibitory effect of a steroidal antiestrogen (EM-170) on estrone-stimulated growth of 7,12-dimethylbenz(a)anthracene (DMBA)-induced mammary carcinoma in the rat
✍ Scribed by Fernand Labrie; Shengmin Li; Claude Labrie; Charles Lévesque; Yves Mérand
- Publisher
- Springer US
- Year
- 1995
- Tongue
- English
- Weight
- 702 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0167-6806
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