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Inhibitors of thromboxane synthase in human platelets

✍ Scribed by Ulf Diczfalusy; Sven Hammarström

Book ID
115907995
Publisher
Elsevier Science
Year
1977
Tongue
English
Weight
273 KB
Volume
82
Category
Article
ISSN
0014-5793

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Picotamide (G 137), a new non prostanoid inhibitor of in vitro arachidonic acid induced platelet aggregation, has been further characterized in in vitro and ex vivo studies. When whole blood was activated with collagen in the presence of picotamide 5 x 10(-4) M, thromboxane B2 production was decreas