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Calmodulin stimulates thromboxane synthesis in human platelets: Studies with thromboxane synthetase inhibitors

✍ Scribed by Patrick Y-K Wong; Wai Yiu Cheung

Book ID
118385686
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
414 KB
Volume
20
Category
Article
ISSN
0163-7827

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The pharmacokinetics and pharmacologic effects of a potent, selective inhibitor of thromboxane synthetase, CV-4151 [(E)-7-phenyl-7-(3-pyridyl)-6-heptenoic acid] on prostanoid formation and platelet aggregation were studied in 42 healthy male volunteers. The drug was well tolerated. After oral admini