The chemical synthesis of 3 beta-p-bromobenzoyloxy-15 beta-methyl-5 alpha,14 beta-cholest-7-en-15 alpha-ol from 15 beta-methyl-5 alpha, 14 beta-cholest-7-ene-3 beta,15 alpha-diol is described. The structure of the former compound was unambiguously determined by X-ray crystallographic analysis. The s
✦ LIBER ✦
Inhibitors of sterol synthesis. 14α-ethyl-5α-cholest-7-ene-3β,15α-diol induces changes in the sterol composition and the morphology of Cho-K1 cells
✍ Scribed by Frederick D. Pinkerton; Akihiro Izumi; George J. Schroepfer Jr.
- Book ID
- 117057785
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- English
- Weight
- 245 KB
- Volume
- 157
- Category
- Article
- ISSN
- 0006-291X
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## Abstract Oxidation of 5α‐cholest‐8(14)‐ene‐3β,7α,15α‐triol with silver carbonate‐celite gave 5α‐cholest‐8(14)‐ene‐7α,15α‐diol‐3‐one in 88% yield. Treatment of the latter compound with tritiated water under basic conditions gave a labeled product which was reduced with lithium tri‐__tert__‐butoxy