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Inhibitors of sterol synthesis. 14α-ethyl-5α-cholest-7-ene-3β,15α-diol induces changes in the sterol composition and the morphology of Cho-K1 cells

✍ Scribed by Frederick D. Pinkerton; Akihiro Izumi; George J. Schroepfer Jr.


Book ID
117057785
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
245 KB
Volume
157
Category
Article
ISSN
0006-291X

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## Abstract Oxidation of 5α‐cholest‐8(14)‐ene‐3β,7α,15α‐triol with silver carbonate‐celite gave 5α‐cholest‐8(14)‐ene‐7α,15α‐diol‐3‐one in 88% yield. Treatment of the latter compound with tritiated water under basic conditions gave a labeled product which was reduced with lithium tri‐__tert__‐butoxy