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Inhibitors of monoamine oxidase VI: Effects of substitution on inhibitory activity of 6(or 8)-substituted β-carbolines

✍ Scribed by Beng T. Ho; Ko-Chin Li; K. E. Walker; L. Wayne Tansey; Patricia M. Kralik; William M. McIsaac

Publisher
John Wiley and Sons
Year
1970
Tongue
English
Weight
497 KB
Volume
59
Category
Article
ISSN
0022-3549

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Several analogs of tetrahydro-p-carboline (I) and 9-methyltetrahydro-p-carboline (VII) with substituents on C-6 or C-8 were synthesized. Methylation of the N-9 position of a tetrahydro p-carboline is generally achieved in the presence of a base. However, the preparations of 8,9-dimethyltetrahydro-p-