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Inhibitors of monoamine oxidase V: Effect of substitution on the transport of tetrahydro-β-carboline analogs to mouse brain

✍ Scribed by Beng T. Ho; G. Edward Fritchie; Patricia M. Kralik; L. Wayne Tansey; K. E. Walker; William M. McIsaac


Publisher
John Wiley and Sons
Year
1969
Tongue
English
Weight
314 KB
Volume
58
Category
Article
ISSN
0022-3549

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Inhibitors of monoamine oxidase IV: 6(or
✍ Beng T. Ho; William M. McIsaac; L. Wayne Tansey 📂 Article 📅 1969 🏛 John Wiley and Sons 🌐 English ⚖ 498 KB

Several analogs of tetrahydro-p-carboline (I) and 9-methyltetrahydro-p-carboline (VII) with substituents on C-6 or C-8 were synthesized. Methylation of the N-9 position of a tetrahydro p-carboline is generally achieved in the presence of a base. However, the preparations of 8,9-dimethyltetrahydro-p-