Naphthazarin derivatives (VIII): Synthes
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Yong Kim; Young-Jae You; Byung-Zun Ahn
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Article
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2001
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John Wiley and Sons
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English
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6-(1-Acyloxyalkyl)-5,8-dimethoxy-1,4-naphthoquinone (DMNQ; 5,8-dimethoxy-1,4-naphthoquinone) derivatives were synthesized and examined for their inhibitory effect on DNA topoisomerase-I (Topo I) and their antiproliferative activity against L1210 cells. The Topo-I inhibitory effect of 6-(1-hydroxyalk