๐”– Bobbio Scriptorium
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Inhibitors of GABA metabolism

โœ Scribed by Brian W. Metcalf


Book ID
115774757
Publisher
Elsevier Science
Year
1979
Tongue
English
Weight
835 KB
Volume
28
Category
Article
ISSN
0006-2952

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๐Ÿ“œ SIMILAR VOLUMES


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## Abstract Stereotaxic injection of kainic acid into rat striatum produces neuronal degeneration and neurochemical alterations resembling Huntington's disease (HD). Since correction of the deficiency in ฮณโ€aminobutyric acid (GABA) in HD may be of therapeutic value, the efficacy of drugs that inhibi

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## Defects in man in four steps of 4aminobutyric acid (GABA) metabolism may interefere with the function of this major inhibitory neurotransmitter. Glutamic acid decarboxylase, 4-aminobutyric acid aminotransferase, succinic semialdehyde dehydrogenase, and homocarnosinase are closely identijied with