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Inhibition of the Hammerhead Ribozyme Cleavage Reaction by Site-Specific Binding of Tb(III)

✍ Scribed by Feig, A. L.


Book ID
121158871
Publisher
American Association for the Advancement of Science
Year
1998
Tongue
English
Weight
408 KB
Volume
279
Category
Article
ISSN
0036-8075

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πŸ“œ SIMILAR VOLUMES


Probing the binding of Tb(III) and Eu(II
✍ Andrew L Feig; Mark Panek; William DeW Horrocks Jr; Olke C Uhlenbeck πŸ“‚ Article πŸ“… 1999 πŸ› Elsevier Science 🌐 English βš– 242 KB

## Background: Divalent metal ions serve as structural as well as catalytic cofactors in the hammerhead ribozyme reaction. the natural cofactor in these reactions is mg(ii), but its spectroscopic silence makes it difficult to study. we previously showed that a single tb(iii) ion inhibits the hammer