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Inhibition of protein phosphatase 1 reverses alcohol induced ciliary dysfunction

✍ Scribed by Price, M.E.; Pavlik, J.A.; Sisson, J.H.; Wyatt, T.A.

Book ID: 126702103
Publisher: Elsevier Science
Year: 2014
Tongue: English
Weight: 47 KB
Volume: 48
Category: Article
ISSN: 0741-8329
DOI: 10.1016/j.alcohol.2014.09.024

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## Abstract Protein phosphatase (PP) activity is associated with the regulation of apoptosis in neutrophils. However, the underlying regulatory mechanism(s) in apoptosis remain unclear. The type of cell death induced by okadaic acid (OA), the inhibitor of PP1 and PP2A, is characterized by apoptotic