𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Inhibition of protein phosphatases induces IGF-1-blocked neurotrophin-insensitive neuronal apoptosis

✍ Scribed by María-Teresa Fernández-Sánchez; Armando García-Rodríguez; Ramón Díaz-Trelles; Antonello Novelli

Book ID
117106734
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
714 KB
Volume
398
Category
Article
ISSN
0014-5793

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Apoptosis of human neutrophils induced b
Apoptosis of human neutrophils induced by protein phosphatase 1/2A inhibition is caspase-independent and serine protease-dependent
✍ Hae-Young Park; Min-Gyu Song; Jun-Sik Lee; Ja-Woong Kim; Jun-O Jin; Joo-In Park; 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 639 KB

## Abstract Protein phosphatase (PP) activity is associated with the regulation of apoptosis in neutrophils. However, the underlying regulatory mechanism(s) in apoptosis remain unclear. The type of cell death induced by okadaic acid (OA), the inhibitor of PP1 and PP2A, is characterized by apoptotic

Inhibition of PI 3-kinase and RAS blocks
Inhibition of PI 3-kinase and RAS blocks IGF-I and insulin-induced uncoupling protein 1 gene expression in brown adipocytes
✍ Teresa Teruel; Angela M. Valverde; Paloma Navarro; Manuel Benito; Margarita Lore 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 324 KB

Fetal brown adipocytes expressed uncoupling protein 1 (UCP1) mRNA, this expression being blunted throughout culture for 24 h in a serum-free medium. At physiological doses, either insulin-like growth factor I (IGF-I) or insulin turned out to be as potent as dibutyryl cAMP (dbcAMP) in increasing UCP1