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Inhibition of protein phosphatase 2A- and protein phosphatase 1-induced tau hyperphosphorylation and impairment of spatial memory retention in rats

โœ Scribed by L Sun; S.Y Liu; X.W Zhou; X.C Wang; R Liu; Q Wang; J.Z Wang


Book ID
117490842
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
209 KB
Volume
118
Category
Article
ISSN
0306-4522

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## Protein phosphatase inhibitors, okadaic acid and Caliculin A, were used to investigate how perturbation of phosphorylation and dephosphorylation processes might affect neurite and synapse structure in cultures of fetal rat hippocampal neurons. Drug treatments induced neuritic tree modification,