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Inhibition of insulin-stimulated glucose transport in rat adipocytes by nucleoside transport inhibitors

✍ Scribed by H.J. Steinfelder; H.G. Joost

Book ID
115921012
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
443 KB
Volume
227
Category
Article
ISSN
0014-5793

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## Abstract We used nigericin, a K^+^/H^+^ exchanger, to test whether glucose transport in 3T3‐L1 adipocytes was modulated by changes in intracellular pH. Our results showed that nigericin increased basal but decreased insulin‐stimulated glucose uptake in a time‐ and dose‐dependent manner. Whereas