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Sepsis inhibits insulin-stimulated glucose transport in isolated rat adipocytes

✍ Scribed by Masahiko Igarashi; Keiichi Yamatani; Norio Fukase; Makoto Daimon; Hiroshi Ohnuma; Hideo Takahashi; Hideo Manaka; Makoto Tominaga; Hideo Sasaki


Book ID
119135222
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
579 KB
Volume
15
Category
Article
ISSN
0168-8227

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Nigericin inhibits insulin-stimulated gl
✍ Chih-Ying Chu; Ying-Shun Kao; Jim C. Fong πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 187 KB

## Abstract We used nigericin, a K^+^/H^+^ exchanger, to test whether glucose transport in 3T3‐L1 adipocytes was modulated by changes in intracellular pH. Our results showed that nigericin increased basal but decreased insulin‐stimulated glucose uptake in a time‐ and dose‐dependent manner. Whereas