101 Combinatorial cancer therapy using a
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A.J. Muller; J.B. DuHadaway; E. Sutanto-Ward; P.S. Donover; G.C. Prendergast
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Article
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2004
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Elsevier Science
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English
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the reduction of 17AAG by NQO1 is relatively stable to autooxidation and formation of the 17AAG hydroquinone may allow for increased levels of 17AAG intracellular drug accumulation via a slow autooxidation process. Another implication of the data is that the 17AAG hydroquinone may represent an alter