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Inhibition of imidazolidinone intermediate formation in the aldol reactions catalyzed by zinc–prolinamide complexes

✍ Scribed by Cecilia Andreu; Teresa Varea; Gregorio Asensio


Book ID
113928932
Publisher
Elsevier Science
Year
2011
Tongue
French
Weight
455 KB
Volume
67
Category
Article
ISSN
0040-4020

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## Abstract A combination of zinc triflate and chiral __C~2~__‐symmetrical prolinamide ligand leads to high enantioselectivities in direct aldol reactions essentially assisted by water. The presence of 5 mol % of the catalyst affords an asymmetric intermolecular aldol reaction between unmodified ke