Inhibition of hypoxia inducible factor-1α (HIF-1α) decreases vascular endothelial growth factor (VEGF) secretion and tumor growth in malignant gliomas
✍ Scribed by Randy L. Jensen; Brian T. Ragel; Kum Whang; David Gillespie
- Publisher
- Springer US
- Year
- 2006
- Tongue
- English
- Weight
- 638 KB
- Volume
- 78
- Category
- Article
- ISSN
- 0167-594X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Neovascularization is involved in beneficial and detrimental processes of tendon pathology. We investigated the influence of repetitive motion on the expression of the most important angiogenic factor, the vascular endothelial growth factor (VEGF) in the 3T3 NIH fibroblast cell line an
## Abstract In oxygenated cells, hypoxia‐inducible factor‐1 (HIF‐1) α subunits are rapidly degraded by a mechanism that involves ubiquitination by the von Hippel–Lindau tumor suppressor E3 ligase complex using 2‐oxoglutarate as a substrate. We examined the effect of 2‐oxoglutarate on the production