## Abstract In oxygenated cells, hypoxia‐inducible factor‐1 (HIF‐1) α subunits are rapidly degraded by a mechanism that involves ubiquitination by the von Hippel–Lindau tumor suppressor E3 ligase complex using 2‐oxoglutarate as a substrate. We examined the effect of 2‐oxoglutarate on the production
✦ LIBER ✦
Bp5250 inhibits vascular endothelial growth factor-induced angiogenesis and HIF-1α expression on endothelial cells
✍ Scribed by Kuan-Ting Lin; Jin-Cherng Lien; Ching-Hu Chung; Sheng-Chu Kuo; Tur-Fu Huang
- Publisher
- Springer-Verlag
- Year
- 2011
- Tongue
- English
- Weight
- 522 KB
- Volume
- 385
- Category
- Article
- ISSN
- 0028-1298
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