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Inhibition of human-type 1 3β-hydroxysteroid deshydrogenase/Δ5-Δ4-isomerase expression using siRNA

✍ Scribed by Mélanie Samson; Fernand Labrie; Van Luu-The


Book ID
116697561
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
195 KB
Volume
94
Category
Article
ISSN
0960-0760

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The activity of 3 beta-hydroxysteroid dehydrogenase delta 4-5 isomerase (3 beta-HSD) was assayed in various tissues microdissected from the freeze-dried human skin of 13 subjects. The sebaceous gland possessed the highest activity of 3 beta-HSD in the skin, while the apocrine sweat gland showed only