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Inhibition of genes expression of SARS coronavirus by synthetic small interfering RNAs

โœ Scribed by SHI, Yi; YANG, De Hua; XIONG, Jie; JIA, Jie; HUANG, Bing; JIN, You Xin


Book ID
110020630
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
309 KB
Volume
15
Category
Article
ISSN
0007-0610

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## Abstract In order to develop a gene therapy to human cytomegalovirus (HCMV), RNA interference (RNAi) was employed to inhibit the expression of HCMV UL122 gene __in vitro__. Recombinant vector pUL122โ€EGFP, which expressed UL122โ€EGFP fusion protein, and recombinant vectors psi122โ€1, psi122โ€2 and p