## Abstract Spleen cells cultured release proteins into the culture medium, some of which shows both binding activity to single stranded DNA (ssβDNA) and inhibitory activity to ^3^Hβthymidine incorporation into cells. The inhibitory protein of DNA synthesis was purified to near homogeneity by ammon
Inhibition of DNA synthesis in erythroleukemic cells by a liver protein fraction
β Scribed by M. P. Viola-Magni; P. Ricerchi
- Publisher
- Springer
- Year
- 1983
- Tongue
- English
- Weight
- 343 KB
- Volume
- 39
- Category
- Article
- ISSN
- 1420-682X
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## Abstract These studies were undertaken to examine the relationship between the inhibition by 5βbromodeoxyuridine (BrdU) of erythroid differentiation in Friend erythroleukemia cells and the incorporation of BrdU into DNA. Experiments were carried out in which the incorporation of BrdU into DNA an
We have isolated and purified a cell surface sialoglycopeptide (SGP) from bovine cerebral cortex cells that previously was shown to be a potent inhibitor of cellular protein synthesis. The following studies were carried out to characterize the potential ability of the SGP to inhibit DNA synthesis an