Inhibition of cytokine function: Potential in autoimmune disease
β Scribed by Michael B. Widmer
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 575 KB
- Volume
- 2
- Category
- Article
- ISSN
- 0958-1669
No coin nor oath required. For personal study only.
β¦ Synopsis
Multiple lines of evidence implicate cytokines in the pathogenesis of autoimmune and inflammatory diseases. Neutralization of the biological activities of cytokines by interfering with ligand binding to specific cell-surface cytokine receptors thus represents an approach to controlling such diseases. Several agents, including novel, receptor-based antagonists, are being developed and tested in disease models.
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