## Abstract It is known that dibutyryl cyclic AMP (dbcAMP) and theophylline inhibit the spontaneous maturation of isolated mouse oocytes. The present study demonstrates that dbcAMP (0.01 β 1.0 mM) as well as cyclic AMP (cAMP, 10 mM) and a phosphodiesterase inhibitor (IBMX, 0.01 β 1.0 mM) prevent sp
Inhibition of cyclic AMP phosphodiesterase of the rat heart and brain by neurohormone C in vitro
β Scribed by A. A. Galoyan; B. Ya. Gurvits; M. A. Pogosyan
- Publisher
- Springer US
- Year
- 1977
- Tongue
- English
- Weight
- 268 KB
- Volume
- 83
- Category
- Article
- ISSN
- 0007-4888
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## Abstract Cytogenetic data are presented which indicate species differences in the response of oocytes maturing in vitro in the presence of dibutyryl cyclic AMP (dbcAMP). Inhibition of ewe oocyte maturation was noted at germinal vesicle, MI, and MII in the presence of 25β750 ΞΌg/ml of dbcAMP. Cow