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Inhibition of cell growth and telomerase activity in osteosarcoma cells by DN-hTERT

โœ Scribed by Tao Xu; Yaojian Rao; Wentao Zhu; Fengjin Guo

Book ID
107405452
Publisher
Springer-Verlag
Year
2006
Tongue
Chinese
Weight
94 KB
Volume
26
Category
Article
ISSN
0510-9752

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Telomerase is a ribonucleoprotein enzyme which stabilizes chromosomal structure, thereby inducing cellular immortality. Three major subunits composing telomerase complex have been cloned, designated hTR (human telomerase RNA), TP1 (telomerase-associated protein 1), and hTERT (human telomerase revers