Oligomer-mediated modulation of hTERT alternative splicing induces telomerase inhibition and cell growth decline in human prostate cancer cells

2-Methoxyestradiol modulates β-catenin i

2-Methoxyestradiol modulates β-catenin in prostate cancer cells: A possible mediator of 2-methoxyestradiol-induced inhibition of cell growth

✍ Peter J. Van Veldhuizen; Gibanananda Ray; Snigdha Banerjee; Gopal Dhar; Suman Ka 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 French ⚖ 235 KB

2-Methoxyestradiol (2-ME 2 ) is a novel anticancer agent because of its ability to potentiate apoptotic cell death and inhibit cancer cell growth and angiogenesis. The modes of action of this agent, however, have not yet been fully elucidated. In our study, we have investigated whether 2-ME2 is able