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shRNA-targeted hTERT suppress cell proliferation of bladder cancer by inhibiting telomerase activity

✍ Scribed by Lin Zou; Penghui Zhang; Chunli Luo; Zhiguang Tu

Publisher: Springer
Year: 2005
Tongue: English
Weight: 523 KB
Volume: 57
Category: Article
ISSN: 0344-5704
DOI: 10.1007/s00280-005-0056-x

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## Background: Telomerase is an enzyme that can reconstitute the ends (telomeres) of chromosomes after cell division and thus circumvent the cumulative damage that occurs in normal adult somatic cells during successive mitotic cycles. recently, it has been proposed that this enzyme should, therefor