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Inhibition of catechol-O-methyltransferase (COMT) by some plant-derived alkaloids and phenolics

✍ Scribed by Dilek Yalcin; Oguz Bayraktar


Book ID
113804506
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
231 KB
Volume
64
Category
Article
ISSN
1381-1177

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Inhibition of human erythrocyte and gast
✍ E. Schultz; S. Tarpila; A.-C. BΓ€ckstrΓΆm; A. Gordin; E. Nissinen; P. Pohto πŸ“‚ Article πŸ“… 1991 πŸ› Springer 🌐 English βš– 367 KB

The effect of increasing single oral doses of the novel catechol-O-methyltransferase (COMT) inhibitor, nitecapone, on enzyme activity in red cells (RBC) and gastroduodenal COMT activity has been studied in healthy male volunteers. A dose-dependent decrease in RBC COMT activity was seen in all cases