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Inhibition of catechol-O-methyltransferase by gossypol: The effect of plasma peoteins

✍ Scribed by F. Tang; A.Y.F. Tsang; Chung-po Lee; P.Y.D. Wong


Book ID
115843814
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
259 KB
Volume
26
Category
Article
ISSN
0010-7824

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## Abstract The short plasma half‐life limits the antiparkinsonian efficacy of levodopa/carbidopa (LD/CD). Administration of LD/CD with the catechol‐__O__‐methyltransferase inhibitor entacapone in one tablet (LCE) may extend plasma half‐life of LD and thus its effect on motor symptoms in patients w