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Inhibition of Carbonic Anhydrases with Glycosyltriazole Benzene Sulfonamides

โœ Scribed by Wilkinson, Brendan L.; Innocenti, Alessio; Vullo, Daniela; Supuran, Claudiu T.; Poulsen, Sally-Ann


Book ID
111650631
Publisher
American Chemical Society
Year
2008
Tongue
English
Weight
174 KB
Volume
51
Category
Article
ISSN
0022-2623

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A series of sulfonamides was prepared by reaction of sulfanilamide with aryl/alkyl isocyanates. The ureido-substituted benzenesulfonamides showed a very interesting profile for the inhibition of several carbonic anhydrases (CAs, EC 4.2.1.1) such as the human hCA II and three ฮฒ-CAs from pathogenic fu