Inhibition of Bovine Carbonic Anhydrase by New Sulfonamide Compounds
β Scribed by O. Arslan
- Book ID
- 110312350
- Publisher
- Springer
- Year
- 2001
- Tongue
- English
- Weight
- 50 KB
- Volume
- 66
- Category
- Article
- ISSN
- 0006-2979
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π SIMILAR VOLUMES
## Abstract The molecular size is found to play an important role in carbonic anhydrase (CA) inhibition by sulfonamides. Significant correlation is obtained between the inhibitory power of __meta__βsubstituted analogs and the van der Waals volume (__V__~__w__~) of the substitutents. This provides a
## X-ray crystal structures of base-on CNCbl [23] and 5'-deoxyadenosylcobalamin [24] (the CH3Cbl structure has not been determined) support a difference in phosphodiester geometry between CNCbl and an alkylcobalamin. Inhibition of Human Carbonic Anhydrase II by Anions and some 'Neutral' Compounds