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Inhibition of benzodiazepine receptor binding by several tryptophan and indole derivatives

✍ Scribed by Klaus J. Fehske; Walter E. MÜller; Karl L. Platt; Angelika E. Stillbauer


Book ID
115775701
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
465 KB
Volume
30
Category
Article
ISSN
0006-2952

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Certain new (1-15) or previously described (16-25) 1,2,3-triazole derivatives, characterized by a C-benzoyl substituent, were synthesized and tested for their ability to displace [3H]flunitrazepam from bovine brain membrane. Compounds 11a and 9a, bearing neutral and lipophilic substituents (phenethy