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Specific inhibition of benzodiazepine receptor binding by some N-(indol-3-ylglyoxylyl)amino acid derivatives

โœ Scribed by Martini, Claudia; Gervasio, Teresa; Lucacchini, Antonio; Da Settimo, Antonio; Primofiore, Giampaolo; Marini, Anna M.


Book ID
127229739
Publisher
American Chemical Society
Year
1985
Tongue
English
Weight
486 KB
Volume
28
Category
Article
ISSN
0022-2623

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Studies on specific inhibition of benzod
โœ G. Biagi; I. Giorgi; O. Livi; A. Lucacchini; C. Martini; V. Scartoni ๐Ÿ“‚ Article ๐Ÿ“… 1993 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 439 KB

Certain new (1-15) or previously described (16-25) 1,2,3-triazole derivatives, characterized by a C-benzoyl substituent, were synthesized and tested for their ability to displace [3H]flunitrazepam from bovine brain membrane. Compounds 11a and 9a, bearing neutral and lipophilic substituents (phenethy