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Specific inhibition of binding to benzodiazepine receptors by 1, 2, 3-triazole derivatives

โœ Scribed by G. Biagi; O. Livi; A. Lucacchini; C. Martini; V. Scartoni


Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
324 KB
Volume
81
Category
Article
ISSN
0022-3549

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๐Ÿ“œ SIMILAR VOLUMES


Studies on specific inhibition of benzod
โœ G. Biagi; I. Giorgi; O. Livi; A. Lucacchini; C. Martini; V. Scartoni ๐Ÿ“‚ Article ๐Ÿ“… 1993 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 439 KB

Certain new (1-15) or previously described (16-25) 1,2,3-triazole derivatives, characterized by a C-benzoyl substituent, were synthesized and tested for their ability to displace [3H]flunitrazepam from bovine brain membrane. Compounds 11a and 9a, bearing neutral and lipophilic substituents (phenethy