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Inhibition of 3H-spiroperidol binding by an endogenous material from brain

โœ Scribed by Robert A. Lahti; David D. Gay; Craig Barsuhn


Book ID
118322876
Publisher
Elsevier Science
Year
1978
Tongue
English
Weight
132 KB
Volume
53
Category
Article
ISSN
0014-2999

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The supernatant obtained from mouse brain homogenates contains material that inhibits the saturable binding of [3H]nicotine in mouse cerebral cortex. This inhibitory material was further purified by heat denaturation, ultrafiltration through an Amicon PM-10 membrane filter, and gel chromatography on