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Inhibition by an extract of Ocimum sanctum of DNA-binding activity of 7,12-dimethylbenz[a]anthracene in rat hepatocytes in vitro

✍ Scribed by Ritu Prashar; Ashok Kumar; Alan Hewer; Kathleen J Cole; Warren Davis; David H Phillips


Book ID
117469054
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
155 KB
Volume
128
Category
Article
ISSN
0304-3835

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## Abstract 7,12‐Dimethylbenz(a)anthracene and three of its metabolites were tested for carcinogenic activity by in vitro incubation with murine pulmonary tissue for 2 days followed by implantation of the explants into isologous mice. 7‐Hydroxymethyl‐12‐methylbenz(a) anthracene and 12‐hydroxymethyl