## Abstract The influence of age at DMBA administration on (1) susceptibility to mammary tumor development, (2) the proportion of tumors which are ovaryβdependent, and (3) the frequency of spontaneous tumor regression was examined in female Lewis rats between 25 and 200 days of age. Tumor developme
Effect of early inhibition of DNA synthesis by hydroxyurea on 7,12-dimethylbenz(a)anthracene mammary carcinogenesis in the rat
β Scribed by Anne G. Jabara; Felicity C. Wilson; R. J. Fisher
- Publisher
- John Wiley and Sons
- Year
- 1974
- Tongue
- English
- Weight
- 351 KB
- Volume
- 113
- Category
- Article
- ISSN
- 0022-3417
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## Abstract The influence of age at time of DMBA administration on (l) the histopathogenesis and site of mammary tumor origin and (2) the precancerous nature of DMBAβinduced mammary dysplasias was examined in Lewis rats between 25 and 200 days of age. Rats were killed at various times after carcino
Effect of the induction of drug metabolizing enzymes by Sudan I11 on the in vivo and in vitro genotoxicity elicited by 7,12-dimethylbenz(a1anthracene (DMBA) was investigated. A significant suppression of DMBA-induced micronucleated reticulocytes was observed in C57BL/6 mice treated with Sudan I11 in
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